Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSTUP00000012480mutS homolog 4. (852 aa)    
Predicted Functional Partners:
ENSSTUP00000106451
mutS homolog 5.
  
0.999
ENSSTUP00000021126
mutL homolog 3 (E. coli).
  
 0.979
ENSSTUP00000062356
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
  
 0.978
pms1
PMS1 homolog 1, mismatch repair system component.
 
 0.966
blm
BLM RecQ like helicase.
  
 0.966
pms2
PMS1 homolog 2, mismatch repair system component.
 
 0.957
ENSSTUP00000075956
annotation not available
  
 0.951
LOC115191814
DNA repair protein RAD51 homolog 1.
   
 0.945
LOC115174706
DNA repair protein RAD51 homolog A.
   
 0.945
fancm
FA complementation group M.
    
 
 0.935
Your Current Organism:
Salmo trutta
NCBI taxonomy Id: 8032
Other names: S. trutta, river trout
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