ENSGMOP00000000785 protein (Gadus morhua) - STRING interaction network

Nodes:

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second shell of interactors

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Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

ENSGMOP00000000785

Nuclear receptor subfamily 2, group F, member 1a. (411 aa)

Predicted Functional Partners:

ENSGMOP00000011443

0.740

ENSGMOP00000007440

0.725

TADA1

0.683

ENSGMOP00000001035

0.603

ENSGMOP00000015387

0.560

ENSGMOP00000002750

0.558

HSP90B1

0.558

ENSGMOP00000013827

0.551

ENSGMOP00000014233

0.543

ENSGMOP00000010899

0.540

Your Current Organism:

Gadus morhua

NCBI taxonomy Id: 8049
Other names: Atlantic cod, G. morhua

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSGMOP00000000785	ENSGMOP00000001035	ENSGMOP00000000785	ENSGMOP00000001035	Nuclear receptor subfamily 2, group F, member 1a.	Ribosomal protein L9.	0.603
ENSGMOP00000000785	ENSGMOP00000002750	ENSGMOP00000000785	ENSGMOP00000002750	Nuclear receptor subfamily 2, group F, member 1a.	annotation not available	0.558
ENSGMOP00000000785	ENSGMOP00000007440	ENSGMOP00000000785	ENSGMOP00000007440	Nuclear receptor subfamily 2, group F, member 1a.	Nuclear receptor corepressor 2.	0.725
ENSGMOP00000000785	ENSGMOP00000010899	ENSGMOP00000000785	ENSGMOP00000010899	Nuclear receptor subfamily 2, group F, member 1a.	RNA binding motif protein 22.	0.540
ENSGMOP00000000785	ENSGMOP00000011443	ENSGMOP00000000785	ENSGMOP00000011443	Nuclear receptor subfamily 2, group F, member 1a.	annotation not available	0.740
ENSGMOP00000000785	ENSGMOP00000013827	ENSGMOP00000000785	ENSGMOP00000013827	Nuclear receptor subfamily 2, group F, member 1a.	Mediator complex subunit 14.	0.551
ENSGMOP00000000785	ENSGMOP00000014233	ENSGMOP00000000785	ENSGMOP00000014233	Nuclear receptor subfamily 2, group F, member 1a.	Mediator complex subunit 17.	0.543
ENSGMOP00000000785	ENSGMOP00000015387	ENSGMOP00000000785	ENSGMOP00000015387	Nuclear receptor subfamily 2, group F, member 1a.	annotation not available	0.560
ENSGMOP00000000785	HSP90B1	ENSGMOP00000000785	ENSGMOP00000014801	Nuclear receptor subfamily 2, group F, member 1a.	Heat shock protein 90 beta family member 1.	0.558
ENSGMOP00000000785	TADA1	ENSGMOP00000000785	ENSGMOP00000018177	Nuclear receptor subfamily 2, group F, member 1a.	Transcriptional adaptor 1.	0.683
ENSGMOP00000001035	ENSGMOP00000000785	ENSGMOP00000001035	ENSGMOP00000000785	Ribosomal protein L9.	Nuclear receptor subfamily 2, group F, member 1a.	0.603
ENSGMOP00000001035	ENSGMOP00000007440	ENSGMOP00000001035	ENSGMOP00000007440	Ribosomal protein L9.	Nuclear receptor corepressor 2.	0.583
ENSGMOP00000001035	ENSGMOP00000011443	ENSGMOP00000001035	ENSGMOP00000011443	Ribosomal protein L9.	annotation not available	0.583
ENSGMOP00000001035	ENSGMOP00000013827	ENSGMOP00000001035	ENSGMOP00000013827	Ribosomal protein L9.	Mediator complex subunit 14.	0.992
ENSGMOP00000001035	ENSGMOP00000014233	ENSGMOP00000001035	ENSGMOP00000014233	Ribosomal protein L9.	Mediator complex subunit 17.	0.991
ENSGMOP00000001035	TADA1	ENSGMOP00000001035	ENSGMOP00000018177	Ribosomal protein L9.	Transcriptional adaptor 1.	0.583
ENSGMOP00000002750	ENSGMOP00000000785	ENSGMOP00000002750	ENSGMOP00000000785	annotation not available	Nuclear receptor subfamily 2, group F, member 1a.	0.558
ENSGMOP00000007440	ENSGMOP00000000785	ENSGMOP00000007440	ENSGMOP00000000785	Nuclear receptor corepressor 2.	Nuclear receptor subfamily 2, group F, member 1a.	0.725
ENSGMOP00000007440	ENSGMOP00000001035	ENSGMOP00000007440	ENSGMOP00000001035	Nuclear receptor corepressor 2.	Ribosomal protein L9.	0.583
ENSGMOP00000010899	ENSGMOP00000000785	ENSGMOP00000010899	ENSGMOP00000000785	RNA binding motif protein 22.	Nuclear receptor subfamily 2, group F, member 1a.	0.540

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

45

average node degree:

8.18

avg. local clustering coefficient:

0.91

expected number of edges:

12

PPI enrichment p-value:

3.14e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019318

Hexose metabolic process

8 of 45

2.2

5.59

2.34e-13

GO:0006006

Glucose metabolic process

6 of 25

2.33

4.67

2.59e-10

GO:0006096

Glycolytic process

5 of 21

2.33

3.81

2.31e-08

GO:0006094

Gluconeogenesis

3 of 12

2.35

2.26

4.89e-05

GO:0006091

Generation of precursor metabolites and energy

6 of 144

1.57

2.22

7.90e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019200

Carbohydrate kinase activity

4 of 18

2.3

2.59

9.51e-06

GO:0048029

Monosaccharide binding

3 of 13

2.31

1.77

0.00045

GO:0008443

Phosphofructokinase activity

2 of 5

2.55

1.1

0.0097

GO:0008865

Fructokinase activity

2 of 6

2.47

1.09

0.0099

GO:0005536

Glucose binding

2 of 6

2.47

1.09

0.0099

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

8 of 821

0.94

0.85

0.00026

GO:0005737

Cytoplasm

11 of 4126

0.38

0.28

0.0294

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:11825

Glycolysis, and Pentose phosphate pathway

9 of 51

2.2

6.69

1.11e-16

CL:11821

Pentose phosphate pathway, and Glycolysis

10 of 79

2.05

6.23

3.22e-17

CL:11819

Carbohydrate metabolic process, and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

11 of 153

1.81

5.0

3.22e-17

CL:11905

Carbohydrate phosphorylation, and Mannose-6-phosphate isomerase

4 of 11

2.51

3.49

2.11e-07

CL:11829

Pentose phosphate pathway, and Glycolytic process

5 of 37

2.08

3.28

1.04e-07

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00030

Pentose phosphate pathway

6 of 35

2.19

4.63

8.22e-11

map00051

Fructose and mannose metabolism

7 of 58

2.03

4.51

1.93e-11

map00010

Glycolysis / Gluconeogenesis

7 of 79

1.9

3.98

7.39e-11

map01200

Carbon metabolism

7 of 188

1.52

2.48

1.26e-08

map00052

Galactose metabolism

4 of 50

1.85

2.34

6.59e-06

(more ...)

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-70171

Glycolysis

5 of 27

2.22

3.54

5.50e-08

MAP-70326

Glucose metabolism

6 of 135

1.6

2.24

1.04e-06

MAP-71387

Metabolism of carbohydrates

8 of 263

1.43

2.18

4.21e-08

MAP-170822

Regulation of Glucokinase by Glucokinase Regulatory Protein

2 of 5

2.55

1.29

0.0044

MAP-6798695

Neutrophil degranulation

5 of 299

1.17

0.92

0.0025

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0324

Glycolysis

5 of 14

2.5

4.5

1.66e-09

KW-0119

Carbohydrate metabolism

2 of 21

1.93

0.78

0.0340

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03727

Hexokinase

2 of 6

2.47

0.83

0.0303

PF00349

Hexokinase

2 of 6

2.47

0.83

0.0303

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