ENSGMOP00000001705 protein (Gadus morhua) - STRING interaction network

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

ENSGMOP00000001705

UPF3B regulator of nonsense mediated mRNA decay. (468 aa)

Predicted Functional Partners:

UPF2

0.993

UPF1

0.991

ENSGMOP00000007553

0.979

magoh

0.979

ENSGMOP00000007822

0.965

ENSGMOP00000001644

0.964

ENSGMOP00000004293

0.961

ENSGMOP00000007849

0.960

ENSGMOP00000001569

0.957

ENSGMOP00000020560

0.954

Your Current Organism:

Gadus morhua

NCBI taxonomy Id: 8049
Other names: Atlantic cod, G. morhua

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSGMOP00000001569	ENSGMOP00000001644	ENSGMOP00000001569	ENSGMOP00000001644	RNA binding protein S1, serine-rich domain.	Eukaryotic translation initiation factor 4A3.	0.995
ENSGMOP00000001569	ENSGMOP00000001705	ENSGMOP00000001569	ENSGMOP00000001705	RNA binding protein S1, serine-rich domain.	UPF3B regulator of nonsense mediated mRNA decay.	0.957
ENSGMOP00000001569	ENSGMOP00000004293	ENSGMOP00000001569	ENSGMOP00000004293	RNA binding protein S1, serine-rich domain.	annotation not available	0.837
ENSGMOP00000001569	ENSGMOP00000007553	ENSGMOP00000001569	ENSGMOP00000007553	RNA binding protein S1, serine-rich domain.	RAN binding protein 2.	0.715
ENSGMOP00000001569	ENSGMOP00000007822	ENSGMOP00000001569	ENSGMOP00000007822	RNA binding protein S1, serine-rich domain.	SMG5 nonsense mediated mRNA decay factor.	0.686
ENSGMOP00000001569	ENSGMOP00000007849	ENSGMOP00000001569	ENSGMOP00000007849	RNA binding protein S1, serine-rich domain.	RNA binding motif protein 8A.	0.991
ENSGMOP00000001569	ENSGMOP00000020560	ENSGMOP00000001569	ENSGMOP00000020560	RNA binding protein S1, serine-rich domain.	Serine/arginine repetitive matrix 1.	0.981
ENSGMOP00000001569	UPF1	ENSGMOP00000001569	ENSGMOP00000008081	RNA binding protein S1, serine-rich domain.	UPF1 RNA helicase and ATPase.	0.989
ENSGMOP00000001569	UPF2	ENSGMOP00000001569	ENSGMOP00000005927	RNA binding protein S1, serine-rich domain.	UPF2 regulator of nonsense mediated mRNA decay.	0.998
ENSGMOP00000001569	magoh	ENSGMOP00000001569	ENSGMOP00000008116	RNA binding protein S1, serine-rich domain.	Mago homolog, exon junction complex subunit.	0.912
ENSGMOP00000001644	ENSGMOP00000001569	ENSGMOP00000001644	ENSGMOP00000001569	Eukaryotic translation initiation factor 4A3.	RNA binding protein S1, serine-rich domain.	0.995
ENSGMOP00000001644	ENSGMOP00000001705	ENSGMOP00000001644	ENSGMOP00000001705	Eukaryotic translation initiation factor 4A3.	UPF3B regulator of nonsense mediated mRNA decay.	0.964
ENSGMOP00000001644	ENSGMOP00000004293	ENSGMOP00000001644	ENSGMOP00000004293	Eukaryotic translation initiation factor 4A3.	annotation not available	0.998
ENSGMOP00000001644	ENSGMOP00000007553	ENSGMOP00000001644	ENSGMOP00000007553	Eukaryotic translation initiation factor 4A3.	RAN binding protein 2.	0.990
ENSGMOP00000001644	ENSGMOP00000007822	ENSGMOP00000001644	ENSGMOP00000007822	Eukaryotic translation initiation factor 4A3.	SMG5 nonsense mediated mRNA decay factor.	0.785
ENSGMOP00000001644	ENSGMOP00000007849	ENSGMOP00000001644	ENSGMOP00000007849	Eukaryotic translation initiation factor 4A3.	RNA binding motif protein 8A.	0.999
ENSGMOP00000001644	ENSGMOP00000020560	ENSGMOP00000001644	ENSGMOP00000020560	Eukaryotic translation initiation factor 4A3.	Serine/arginine repetitive matrix 1.	0.924
ENSGMOP00000001644	UPF1	ENSGMOP00000001644	ENSGMOP00000008081	Eukaryotic translation initiation factor 4A3.	UPF1 RNA helicase and ATPase.	0.952
ENSGMOP00000001644	UPF2	ENSGMOP00000001644	ENSGMOP00000005927	Eukaryotic translation initiation factor 4A3.	UPF2 regulator of nonsense mediated mRNA decay.	0.893
ENSGMOP00000001644	magoh	ENSGMOP00000001644	ENSGMOP00000008116	Eukaryotic translation initiation factor 4A3.	Mago homolog, exon junction complex subunit.	0.998

page 1 of 6

Network Stats

number of nodes:

6

number of edges:

9

average node degree:

3

avg. local clustering coefficient:

0.8

expected number of edges:

8

PPI enrichment p-value:

0.412

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000387

Spliceosomal snRNP assembly

4 of 30

2.45

2.86

3.49e-06

GO:0040031

snRNA modification

3 of 8

2.9

2.63

1.54e-05

GO:0008380

RNA splicing

6 of 351

1.55

1.92

9.26e-06

GO:0000398

mRNA splicing, via spliceosome

5 of 229

1.66

1.86

4.08e-05

GO:0016071

mRNA metabolic process

7 of 575

1.41

1.78

3.85e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0017069

snRNA binding

7 of 39

2.58

6.59

6.85e-14

GO:0017070

U6 snRNA binding

4 of 8

3.02

4.21

1.86e-08

GO:0003723

RNA binding

9 of 1208

1.19

1.57

1.37e-07

GO:0097322

7SK snRNA binding

2 of 5

2.92

1.46

0.0023

GO:1901363

Heterocyclic compound binding

10 of 6430

0.51

0.37

0.0105

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030532

Small nuclear ribonucleoprotein complex

5 of 59

2.25

3.5

8.06e-08

GO:0046540

U4/U6 x U5 tri-snRNP complex

4 of 32

2.42

3.19

6.88e-07

GO:0015030

Cajal body

4 of 36

2.37

3.17

6.88e-07

GO:0071005

U2-type precatalytic spliceosome

4 of 48

2.24

2.95

1.35e-06

GO:1990904

Ribonucleoprotein complex

7 of 598

1.39

1.89

6.88e-07

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:19743

Regulation of protein localization to Cajal body, and U6 snRNA 3-end binding

4 of 6

3.15

4.14

2.82e-08

CL:18977

Small nuclear ribonucleoprotein complex, and snRNA binding

5 of 66

2.2

3.24

2.60e-07

CL:19047

Spliceosomal tri-snRNP complex assembly, and U4/U6 x U5 tri-snRNP complex

3 of 10

2.8

2.65

1.34e-05

CL:18979

Spliceosomal snRNP complex, and snRNA binding

4 of 60

2.15

2.46

1.20e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03040

Spliceosome

4 of 266

1.5

1.26

0.0011

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72203

Processing of Capped Intron-Containing Pre-mRNA

5 of 391

1.43

1.31

0.00051

MAP-8953854

Metabolism of RNA

7 of 946

1.19

1.21

9.46e-05

MAP-72163

mRNA Splicing - Major Pathway

4 of 272

1.49

1.09

0.0034

MAP-72172

mRNA Splicing

4 of 296

1.45

1.06

0.0036

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1990904

Ribonucleoprotein complex

7 of 447

1.52

2.16

5.13e-07

GOCC:0005634

Nucleus

8 of 3501

0.68

0.43

0.0232

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