ENSGMOP00000014552 protein (Gadus morhua) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSGMOP00000014552

annotation not available (232 aa)

Predicted Functional Partners:

ENSGMOP00000011764

0.797

ENSGMOP00000011775

0.797

ENSGMOP00000021242

0.797

ENSGMOP00000021437

0.796

ENSGMOP00000002677

0.788

ENSGMOP00000009026

0.788

ENSGMOP00000017608

0.788

ENSGMOP00000001272

0.688

ENSGMOP00000002415

0.688

PTK7

0.674

Your Current Organism:

Gadus morhua

NCBI taxonomy Id: 8049
Other names: Atlantic cod, G. morhua

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSGMOP00000001272	ENSGMOP00000014552	ENSGMOP00000001272	ENSGMOP00000014552	Coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1.	annotation not available	0.688
ENSGMOP00000001272	PTK7	ENSGMOP00000001272	ENSGMOP00000012396	Coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1.	Protein tyrosine kinase 7 (inactive).	0.445
ENSGMOP00000002415	ENSGMOP00000011775	ENSGMOP00000002415	ENSGMOP00000011775	annotation not available	Coagulation factor II (thrombin) receptor.	0.774
ENSGMOP00000002415	ENSGMOP00000014552	ENSGMOP00000002415	ENSGMOP00000014552	annotation not available	annotation not available	0.688
ENSGMOP00000002415	PTK7	ENSGMOP00000002415	ENSGMOP00000012396	annotation not available	Protein tyrosine kinase 7 (inactive).	0.445
ENSGMOP00000002677	ENSGMOP00000009026	ENSGMOP00000002677	ENSGMOP00000009026	Macrophage stimulating 1 receptor b.	MET proto-oncogene, receptor tyrosine kinase.	0.883
ENSGMOP00000002677	ENSGMOP00000014552	ENSGMOP00000002677	ENSGMOP00000014552	Macrophage stimulating 1 receptor b.	annotation not available	0.788
ENSGMOP00000002677	ENSGMOP00000017608	ENSGMOP00000002677	ENSGMOP00000017608	Macrophage stimulating 1 receptor b.	Macrophage stimulating 1 receptor a.	0.886
ENSGMOP00000002677	PTK7	ENSGMOP00000002677	ENSGMOP00000012396	Macrophage stimulating 1 receptor b.	Protein tyrosine kinase 7 (inactive).	0.917
ENSGMOP00000009026	ENSGMOP00000002677	ENSGMOP00000009026	ENSGMOP00000002677	MET proto-oncogene, receptor tyrosine kinase.	Macrophage stimulating 1 receptor b.	0.883
ENSGMOP00000009026	ENSGMOP00000014552	ENSGMOP00000009026	ENSGMOP00000014552	MET proto-oncogene, receptor tyrosine kinase.	annotation not available	0.788
ENSGMOP00000009026	ENSGMOP00000017608	ENSGMOP00000009026	ENSGMOP00000017608	MET proto-oncogene, receptor tyrosine kinase.	Macrophage stimulating 1 receptor a.	0.883
ENSGMOP00000009026	PTK7	ENSGMOP00000009026	ENSGMOP00000012396	MET proto-oncogene, receptor tyrosine kinase.	Protein tyrosine kinase 7 (inactive).	0.917
ENSGMOP00000011764	ENSGMOP00000011775	ENSGMOP00000011764	ENSGMOP00000011775	Coagulation factor II (thrombin) receptor-like 2.	Coagulation factor II (thrombin) receptor.	0.501
ENSGMOP00000011764	ENSGMOP00000014552	ENSGMOP00000011764	ENSGMOP00000014552	Coagulation factor II (thrombin) receptor-like 2.	annotation not available	0.797
ENSGMOP00000011764	PTK7	ENSGMOP00000011764	ENSGMOP00000012396	Coagulation factor II (thrombin) receptor-like 2.	Protein tyrosine kinase 7 (inactive).	0.445
ENSGMOP00000011775	ENSGMOP00000002415	ENSGMOP00000011775	ENSGMOP00000002415	Coagulation factor II (thrombin) receptor.	annotation not available	0.774
ENSGMOP00000011775	ENSGMOP00000011764	ENSGMOP00000011775	ENSGMOP00000011764	Coagulation factor II (thrombin) receptor.	Coagulation factor II (thrombin) receptor-like 2.	0.501
ENSGMOP00000011775	ENSGMOP00000014552	ENSGMOP00000011775	ENSGMOP00000014552	Coagulation factor II (thrombin) receptor.	annotation not available	0.797
ENSGMOP00000011775	PTK7	ENSGMOP00000011775	ENSGMOP00000012396	Coagulation factor II (thrombin) receptor.	Protein tyrosine kinase 7 (inactive).	0.445

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

22

PPI enrichment p-value:

2.95e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 328

1.8

4.86

1.46e-16

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 159

2.07

6.34

2.75e-17

GO:0019843

rRNA binding

3 of 51

2.05

1.36

0.0024

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 184

2.01

5.98

5.37e-17

GO:0044391

Ribosomal subunit

4 of 135

1.75

1.71

0.00019

GO:0015935

Small ribosomal subunit

3 of 46

2.09

1.69

0.00050

GO:0022627

Cytosolic small ribosomal subunit

2 of 18

2.32

1.12

0.0086

GO:1990904

Ribonucleoprotein complex

5 of 555

1.23

1.04

0.0012

(more ...)

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:28942070

(2017) Ryanodine receptor and FK506 binding protein 1 in the Atlantic killifish (Fundulus heteroclitus): A phylogenetic and population-based comparison.

2 of 9

2.62

0.93

0.0209

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:15235