ENSGMOP00000017166 protein (Gadus morhua) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSGMOP00000017166

AFG1 like ATPase b. (425 aa)

Predicted Functional Partners:

ENSGMOP00000007427

0.516

ENSGMOP00000006997

0.503

ENSGMOP00000005311

0.437

ENSGMOP00000005330

0.437

ENSGMOP00000005370

0.437

ENSGMOP00000018570

0.408

Your Current Organism:

Gadus morhua

NCBI taxonomy Id: 8049
Other names: Atlantic cod, G. morhua

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structured XML interaction data, according to the 'PSI-MI' data standard

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
ENSGMOP00000005311	ENSGMOP00000005330	annotation not available	annotation not available	0.998
ENSGMOP00000005311	ENSGMOP00000005370	annotation not available	annotation not available	0.999
ENSGMOP00000005311	ENSGMOP00000017166	annotation not available	AFG1 like ATPase b.	0.437
ENSGMOP00000005330	ENSGMOP00000005311	annotation not available	annotation not available	0.998
ENSGMOP00000005330	ENSGMOP00000005370	annotation not available	annotation not available	0.998
ENSGMOP00000005330	ENSGMOP00000017166	annotation not available	AFG1 like ATPase b.	0.437
ENSGMOP00000005370	ENSGMOP00000005311	annotation not available	annotation not available	0.999
ENSGMOP00000005370	ENSGMOP00000005330	annotation not available	annotation not available	0.998
ENSGMOP00000005370	ENSGMOP00000017166	annotation not available	AFG1 like ATPase b.	0.437
ENSGMOP00000006997	ENSGMOP00000017166	Succinate dehydrogenase complex, subunit C, integral membrane protein.	AFG1 like ATPase b.	0.503
ENSGMOP00000007427	ENSGMOP00000017166	Zinc finger DHHC-type containing 17.	AFG1 like ATPase b.	0.516
ENSGMOP00000017166	ENSGMOP00000005311	AFG1 like ATPase b.	annotation not available	0.437
ENSGMOP00000017166	ENSGMOP00000005330	AFG1 like ATPase b.	annotation not available	0.437
ENSGMOP00000017166	ENSGMOP00000005370	AFG1 like ATPase b.	annotation not available	0.437
ENSGMOP00000017166	ENSGMOP00000006997	AFG1 like ATPase b.	Succinate dehydrogenase complex, subunit C, integral membrane protein.	0.503
ENSGMOP00000017166	ENSGMOP00000007427	AFG1 like ATPase b.	Zinc finger DHHC-type containing 17.	0.516
ENSGMOP00000017166	ENSGMOP00000018570	AFG1 like ATPase b.	Dolichyl-phosphate mannosyltransferase subunit 1, catalytic.	0.408
ENSGMOP00000018570	ENSGMOP00000017166	Dolichyl-phosphate mannosyltransferase subunit 1, catalytic.	AFG1 like ATPase b.	0.408

Network Stats

number of nodes:

10

number of edges:

19

average node degree:

3.8

avg. local clustering coefficient:

0.854

expected number of edges:

9

PPI enrichment p-value:

0.00352

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 107

1.67

4.11

8.96e-16

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 54

1.97

6.23

4.86e-19

GO:0019843

rRNA binding

9 of 42

1.99

5.37

6.93e-15

GO:0003723

RNA binding

10 of 109

1.62

3.63

7.15e-14

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 58

1.94

6.13

2.00e-19

GO:0044391

Ribosomal subunit

5 of 15

2.19

3.89

6.52e-09

GO:0015935

Small ribosomal subunit

3 of 7

2.29

2.46

1.74e-05

GO:0015934

Large ribosomal subunit

2 of 8

2.06

1.32

0.0029

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1728

Ribosome, and Translation regulator activity

11 of 69

1.86

5.4

8.21e-18

CL:1730

rRNA-binding, and EFG, domain V

8 of 33

2.05

5.21

1.32e-13

CL:1734

rRNA-binding

7 of 28

2.06

4.66

1.08e-11

CL:1771

Mixed, incl. Small ribosomal subunit, and K Homology domain, type 2

4 of 8

2.36

3.24

4.63e-07

CL:1835

Translation elongation factor EF1B/ribosomal protein S6, and Structural constituent of ribosome

3 of 6

2.36

2.28

4.65e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

11 of 59

1.93

6.08

1.99e-19

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

9 of 43

1.98

5.3

9.13e-15

GOCC:0044391

Ribosomal subunit

6 of 19

2.16

4.37

3.16e-10

GOCC:0015935

Small ribosomal subunit

5 of 10

2.36

4.35

1.71e-09

GOCC:0022627

Cytosolic small ribosomal subunit

4 of 8

2.36

3.43

1.81e-07

GOCC:0043229

Intracellular organelle

11 of 417

1.08

1.5

1.91e-10

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

11 of 56

1.96

6.22

1.94e-19

KW-0699

rRNA-binding

9 of 40

2.01

5.64

1.31e-15

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