STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSFHEP00000000227Cullin 1b; Belongs to the cullin family. (471 aa)    
Predicted Functional Partners:
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
    
 0.999
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
   
 0.999
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.999
fbxw11
F-box and WD repeat domain containing 11b.
    
 0.998
ubxn7
UBX domain protein 7.
   
 0.996
fbxl17
F-box and leucine-rich repeat protein 17.
    
 0.990
cops5
COP9 signalosome subunit 5.
   
 0.988
LOC105930277
NEDD8 ubiquitin like modifier.
    
 0.988
nedd8
NEDD8.
    
 0.988
LOC105938564
Cyclin-dependent kinase inhibitor 1Bb.
    
 0.977
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.