STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cnn3Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (329 aa)    
Predicted Functional Partners:
wdr90
WD repeat domain 90.
    
 
 0.899
LOC110368474
Enkurin domain-containing protein.
   
 
 0.676
WDR1
WD repeat domain 1.
   
 
 0.666
efhc1
EF-hand domain (C-terminal) containing 1.
    
 
 0.666
efhb
Uncharacterized protein.
    
   0.659
ENSFHEP00000021313
Uncharacterized protein.
      
 0.637
ENSFHEP00000013903
PARK2 co-regulated.
    
 
 0.632
PACRG
Parkin coregulated.
    
 
 0.632
LOC105935293
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
   
  
 0.624
sgcd
Sarcoglycan, delta (dystrophin-associated glycoprotein).
      
 0.613
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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