STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cep135Centrosomal protein 135. (1105 aa)    
Predicted Functional Partners:
LOC105920702
Intersectin 2b.
   
 0.999
ENSFHEP00000007368
Uncharacterized protein.
   
 0.999
ENSFHEP00000025972
Uncharacterized protein.
   
 0.999
LOC105939779
Flocculation protein FLO11.
   
 0.937
itsn1
Intersectin 1 (SH3 domain protein).
   
 0.937
gak
Cyclin G associated kinase.
   
 0.892
plk4
Polo-like kinase 4 (Drosophila).
   
 0.837
LOC105939792
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
 0.834
cenpj
Centromere protein J.
   
 
 0.823
PLK1
Serine/threonine-protein kinase PLK.
   
 0.795
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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