STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbc1d2bTBC1 domain family, member 2B. (1029 aa)    
Predicted Functional Partners:
nrde2
NRDE-2, necessary for RNA interference, domain containing.
    
 0.793
wdr90
WD repeat domain 90.
    
   0.746
LOC105926030
RAB7a, member RAS oncogene family.
    
 0.725
RAB7A
RAB7A, member RAS oncogene family.
    
 0.725
PLK1
Serine/threonine-protein kinase PLK.
    
 0.711
plk2
Serine/threonine-protein kinase PLK.
    
 0.711
plk3
Serine/threonine-protein kinase PLK.
    
 0.711
plk4
Polo-like kinase 4 (Drosophila).
    
 0.711
armc5
Armadillo repeat containing 5.
    
 0.592
RAB9A
RAB9A, member RAS oncogene family.
    
 0.592
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.