STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF126E3 ubiquitin-protein ligase RNF126. (313 aa)    
Predicted Functional Partners:
ENSFHEP00000019799
Ubiquitin-like domain-containing protein.
    
 
 0.955
rspo2
R-spondin 2.
    
 0.847
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.792
rps27a
Ribosomal protein S27a.
    
 0.768
lgr4
Leucine-rich repeat containing G protein-coupled receptor 4.
    
 0.768
LOC105927749
R-spondin 3.
    
 0.725
get4
Guided entry of tail-anchored proteins factor 4.
   
 
 0.710
ENSFHEP00000026593
R-spondin 4.
    
 0.704
suv39h1
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
    
  0.639
trip12
Thyroid hormone receptor interactor 12.
     
 0.617
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.