STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bhlhe23Basic helix-loop-helix family, member e23. (227 aa)    
Predicted Functional Partners:
ASCL4
Achaete-scute family bHLH transcription factor 4.
   
 
 0.602
LOC105919486
Gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.530
bhlha9
Basic helix-loop-helix family, member a9.
      
 0.526
gart
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
      
 0.493
ENSFHEP00000005963
BHLH domain-containing protein.
   
 
 0.470
tcf12
Transcription factor 12.
    
 
 0.433
LOC105934577
Transcription factor 3a.
    
 
 0.433
TCF4
Transcription factor 4.
    
 
 0.433
tcf3
Transcription factor 3b.
    
 
 0.433
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.