STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brat1BRCA1-associated ATM activator 1. (859 aa)    
Predicted Functional Partners:
e4f1
E4F transcription factor 1.
   
    0.731
brca1
Breast cancer 1, early onset.
    
 
 0.715
brap
BRCA1 associated protein.
      
 0.637
PKP1
Plakophilin-1.
      
 0.527
LOC105928075
Plakophilin 1b.
      
 0.527
tonsl
Tonsoku-like, DNA repair protein.
      
 0.501
telo2
TEL2, telomere maintenance 2, homolog (S. cerevisiae).
   
    0.436
tp53bp1
Tumor protein p53 binding protein, 1.
      
 0.422
LOC105922837
BRCT domain-containing protein.
    
 
 0.421
entpd2
Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family.
      
 0.412
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.