STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105932345Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (466 aa)    
Predicted Functional Partners:
ACO2
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.991
aco1
Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family.
  
 0.990
LOC105919972
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.990
idh3a
Isocitrate dehydrogenase (NAD(+)) 3 alpha.
  
 0.988
LOC105915617
Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide).
  
 
 0.980
got2
Aspartate aminotransferase.
   
 0.978
OGDH
Oxoglutarate dehydrogenase.
  
 
 0.978
cs
Citrate synthase; Belongs to the citrate synthase family.
  
 0.969
idh1
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 
0.969
GOT1
Aspartate aminotransferase.
   
 0.968
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.