STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EVCEllis-van Creveld syndrome protein. (969 aa)    
Predicted Functional Partners:
EVC2
EvC ciliary complex subunit 2.
  
 
 0.994
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.976
LOC105920223
Malate synthase-like.
   
 
 0.816
efcab7
EF-hand calcium binding domain 7.
    
 0.672
brca1
Breast cancer 1, early onset.
  
 
 0.668
HECTD4
HECT domain E3 ubiquitin protein ligase 4.
    
 0.650
gga3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3a.
      
 0.635
LOC105921795
Uncharacterized protein.
    
 0.622
dhcr24
24-dehydrocholesterol reductase.
    
 
 0.549
espl1
Extra spindle pole bodies like 1, separase.
    
 0.540
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.