STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)    
Predicted Functional Partners:
LOC105929858
Polymerase (DNA directed), epsilon 2.
    
 0.998
pole
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
    
 0.998
pole3
Uncharacterized protein.
    
 0.998
pola1
DNA polymerase.
    
 0.922
pold1
DNA polymerase.
    
 0.884
rev3l
REV3 like, DNA directed polymerase zeta catalytic subunit.
    
 0.872
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
    
 0.851
pold2
Polymerase (DNA directed), delta 2, regulatory subunit.
     
 0.807
rfc1
Replication factor C subunit 1.
     
 0.805
pola2
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
     
 0.797
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.