STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)    
Predicted Functional Partners:
gtf2h3
General transcription factor IIH, polypeptide 3.
    
 0.999
ercc2
TFIIH basal transcription factor complex helicase XPD subunit.
    
 0.999
ercc3
Excision repair cross-complementation group 3.
   
 0.999
gtf2h4
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.999
mnat1
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
    
 0.998
gtf2e1
General transcription factor IIE, polypeptide 1, alpha.
   
 0.998
gtf2e2
General transcription factor IIE, polypeptide 2, beta.
    
 0.997
gtf2h5
General transcription factor IIH, polypeptide 5.
    
 0.995
ccnh
Cyclin H; Belongs to the cyclin family.
    
 0.994
ENSFHEP00000020929
General transcription factor IIH, polypeptide 2.
    
 0.993
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.