STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arih1RBR-type E3 ubiquitin transferase. (349 aa)    
Predicted Functional Partners:
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.971
rps27a
Ribosomal protein S27a.
    
 0.966
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.965
ENSFHEP00000000227
Cullin 1b; Belongs to the cullin family.
   
 0.954
LOC105930277
NEDD8 ubiquitin like modifier.
    
 0.922
nedd8
NEDD8.
    
 0.922
LOC105923405
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.883
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.883
eif4e2
Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.
    
 0.835
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.835
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.