DDX5 protein (Fundulus heteroclitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DDX5

DEAD-box helicase 5; Belongs to the DEAD box helicase family. (632 aa)

Predicted Functional Partners:

pes1

0.941

drosha

0.912

LOC105929919

0.899

gnl3

0.897

sf3b1

0.883

ebna1bp2

0.879

mtrex

0.855

wdr12

0.845

ENSFHEP00000009615

0.837

dkc1

0.831

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX5	ENSFHEP00000009615	ENSFHEP00000004623	ENSFHEP00000009615	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	DRBM domain-containing protein.	0.837
DDX5	LOC105929919	ENSFHEP00000004623	ENSFHEP00000009792	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	ATP-dependent RNA helicase DDX17, putative; Belongs to the DEAD box helicase family.	0.899
DDX5	dkc1	ENSFHEP00000004623	ENSFHEP00000003722	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Dyskeratosis congenita 1, dyskerin.	0.831
DDX5	drosha	ENSFHEP00000004623	ENSFHEP00000002866	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Drosha ribonuclease III.	0.912
DDX5	ebna1bp2	ENSFHEP00000004623	ENSFHEP00000021610	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	rRNA-processing protein EBP2, putative.	0.879
DDX5	gnl3	ENSFHEP00000004623	ENSFHEP00000019010	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Guanine nucleotide binding protein-like 3 (nucleolar).	0.897
DDX5	mtrex	ENSFHEP00000004623	ENSFHEP00000020958	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Mtr4 exosome RNA helicase.	0.855
DDX5	pes1	ENSFHEP00000004623	ENSFHEP00000011494	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.941
DDX5	sf3b1	ENSFHEP00000004623	ENSFHEP00000012829	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Splicing factor 3b, subunit 1.	0.883
DDX5	wdr12	ENSFHEP00000004623	ENSFHEP00000025629	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.845
ENSFHEP00000009615	DDX5	ENSFHEP00000009615	ENSFHEP00000004623	DRBM domain-containing protein.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.837
ENSFHEP00000009615	LOC105929919	ENSFHEP00000009615	ENSFHEP00000009792	DRBM domain-containing protein.	ATP-dependent RNA helicase DDX17, putative; Belongs to the DEAD box helicase family.	0.837
ENSFHEP00000009615	drosha	ENSFHEP00000009615	ENSFHEP00000002866	DRBM domain-containing protein.	Drosha ribonuclease III.	0.626
ENSFHEP00000009615	mtrex	ENSFHEP00000009615	ENSFHEP00000020958	DRBM domain-containing protein.	Mtr4 exosome RNA helicase.	0.755
ENSFHEP00000009615	sf3b1	ENSFHEP00000009615	ENSFHEP00000012829	DRBM domain-containing protein.	Splicing factor 3b, subunit 1.	0.686
LOC105929919	DDX5	ENSFHEP00000009792	ENSFHEP00000004623	ATP-dependent RNA helicase DDX17, putative; Belongs to the DEAD box helicase family.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.899
LOC105929919	ENSFHEP00000009615	ENSFHEP00000009792	ENSFHEP00000009615	ATP-dependent RNA helicase DDX17, putative; Belongs to the DEAD box helicase family.	DRBM domain-containing protein.	0.837
LOC105929919	dkc1	ENSFHEP00000009792	ENSFHEP00000003722	ATP-dependent RNA helicase DDX17, putative; Belongs to the DEAD box helicase family.	Dyskeratosis congenita 1, dyskerin.	0.831
LOC105929919	drosha	ENSFHEP00000009792	ENSFHEP00000002866	ATP-dependent RNA helicase DDX17, putative; Belongs to the DEAD box helicase family.	Drosha ribonuclease III.	0.912
LOC105929919	ebna1bp2	ENSFHEP00000009792	ENSFHEP00000021610	ATP-dependent RNA helicase DDX17, putative; Belongs to the DEAD box helicase family.	rRNA-processing protein EBP2, putative.	0.879