Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSFHEP00000004635C2-set_2 domain-containing protein. (284 aa)    
Predicted Functional Partners:
LOC105929009
Cell adhesion molecule 1a.
    
  0.838
ENSFHEP00000022670
Cell adhesion molecule 1b.
    
  0.838
afdn
Afadin, adherens junction formation factor a.
    
 0.692
CASK
Uncharacterized protein; Belongs to the MAGUK family.
    
  0.567
LOC105921523
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
    
  0.567
jam2
Junctional adhesion molecule 2a.
    
  0.486
LOC105930123
Junctional adhesion molecule 3b.
    
  0.485
LOC105919838
Carcinoembryonic antigen-related cell adhesion molecule 1.
     
  0.458
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2.
     
  0.458
tomm40
Translocase of outer mitochondrial membrane 40 homolog (yeast).
    
  0.430
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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