STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
egln1Egl-9 family hypoxia-inducible factor 1a. (234 aa)    
Predicted Functional Partners:
ENSFHEP00000005022
Fe2OG dioxygenase domain-containing protein.
 
      0.900
LOC105933321
Endothelial PAS domain protein 1b.
    
 0.846
hif3alpha
Hypoxia inducible factor 1 subunit alpha, like.
    
 0.846
epas1
Uncharacterized protein.
    
 0.846
hif1a
Hypoxia inducible factor 1 subunit alpha a.
    
 0.846
NPAS3
Neuronal PAS domain protein 3.
    
 0.807
ENSFHEP00000030853
Neuronal PAS domain protein 1.
    
 0.807
LOC105927179
Von Hippel-Lindau tumor suppressor.
    
 0.806
eloc
Elongin C paralog a; Belongs to the SKP1 family.
     
 0.710
cul2
Cullin 2; Belongs to the cullin family.
     
 0.673
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.