STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105927744Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)    
Predicted Functional Partners:
LOC105935986
GNAS complex locus.
    
 0.953
gnas
Uncharacterized protein.
    
 0.953
GNAL
G protein subunit alpha L.
    
 0.930
LOC105921230
Uncharacterized protein.
    
 0.930
pde4b
Phosphodiesterase.
    
 0.923
ENSFHEP00000030889
Phosphodiesterase.
    
 0.923
pde4d
Phosphodiesterase.
    
 0.922
ENSFHEP00000018584
Phosphodiesterase.
    
 0.922
LOC105937320
Phosphodiesterase.
    
 0.920
LOC105935576
Uncharacterized protein.
    
 0.920
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.