STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSFHEP00000005390Histone H2A; Belongs to the histone H2A family. (234 aa)    
Predicted Functional Partners:
mysm1
Myb-like, SWIRM and MPN domains 1.
    
 0.995
kdm6a
Lysine (K)-specific demethylase 6A.
    
 0.821
LOC105932189
Lysine (K)-specific demethylase 6B, b.
    
 0.821
LOC105940360
Lysine (K)-specific demethylase 6B, a.
    
 0.821
LOC105921518
Lysine (K)-specific demethylase 6A, like.
    
 0.821
smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5.
    
 0.820
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.813
rps27a
Ribosomal protein S27a.
   
  0.806
HIST1H4J
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.798
ENSFHEP00000005562
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.798
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.