STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ncor1Nuclear receptor corepressor 1. (2343 aa)    
Predicted Functional Partners:
HDAC3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.977
LOC105924034
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.
    
 0.973
tada3
Transcriptional adaptor 3 (NGG1 homolog, yeast)-like.
    
 0.972
taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.
    
 0.972
taf10
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
    
 0.969
trrap
Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
   
 0.965
taf6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor.
    
 0.963
supt3h
Uncharacterized protein.
    
 0.961
sgf29
SAGA complex associated factor 29.
    
 0.961
supt20h
SPT20 homolog, SAGA complex component.
    
 0.954
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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