STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA5Pleckstrin homology domain containing A5. (1163 aa)    
Predicted Functional Partners:
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.695
rps27a
Ribosomal protein S27a.
    
 0.680
lats2
Serine/threonine-protein kinase LATS2.
    
 0.661
lats1
Large tumor suppressor kinase 1.
    
 0.661
LOC105938003
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.649
LOC105920702
Intersectin 2b.
    
  0.643
ENSFHEP00000007368
Uncharacterized protein.
    
  0.643
ENSFHEP00000025972
Uncharacterized protein.
    
  0.643
sav1
Salvador family WW domain containing protein 1.
    
 0.623
fbxw11
F-box and WD repeat domain containing 11b.
    
 0.587
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.