node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSFHEP00000025839 | LOC105917111 | ENSFHEP00000025839 | ENSFHEP00000007962 | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.971 |
ENSFHEP00000025839 | LOC105920223 | ENSFHEP00000025839 | ENSFHEP00000023663 | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. | Malate synthase-like. | 0.978 |
ENSFHEP00000025839 | LOC105920747 | ENSFHEP00000025839 | ENSFHEP00000006284 | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. | Enoyl-CoA delta isomerase 2. | 0.978 |
ENSFHEP00000025839 | acadsb | ENSFHEP00000025839 | ENSFHEP00000009973 | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. | Acyl-CoA dehydrogenase short/branched chain. | 0.981 |
ENSFHEP00000025839 | acat1 | ENSFHEP00000025839 | ENSFHEP00000012277 | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.985 |
ENSFHEP00000025839 | acox3 | ENSFHEP00000025839 | ENSFHEP00000023696 | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.990 |
ENSFHEP00000025839 | cs | ENSFHEP00000025839 | ENSFHEP00000005253 | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. | Citrate synthase; Belongs to the citrate synthase family. | 0.709 |
ENSFHEP00000025839 | hadh | ENSFHEP00000025839 | ENSFHEP00000024604 | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. | Hydroxyacyl-CoA dehydrogenase. | 0.973 |
ENSFHEP00000025839 | hadha | ENSFHEP00000025839 | ENSFHEP00000000654 | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b. | 0.964 |
ENSFHEP00000025839 | oxct1 | ENSFHEP00000025839 | ENSFHEP00000016432 | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.969 |
LOC105917111 | ENSFHEP00000025839 | ENSFHEP00000007962 | ENSFHEP00000025839 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. | 0.971 |
LOC105917111 | LOC105920747 | ENSFHEP00000007962 | ENSFHEP00000006284 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Enoyl-CoA delta isomerase 2. | 0.747 |
LOC105917111 | acat1 | ENSFHEP00000007962 | ENSFHEP00000012277 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.997 |
LOC105917111 | cs | ENSFHEP00000007962 | ENSFHEP00000005253 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Citrate synthase; Belongs to the citrate synthase family. | 0.965 |
LOC105917111 | hadh | ENSFHEP00000007962 | ENSFHEP00000024604 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Hydroxyacyl-CoA dehydrogenase. | 0.958 |
LOC105917111 | hadha | ENSFHEP00000007962 | ENSFHEP00000000654 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b. | 0.822 |
LOC105917111 | oxct1 | ENSFHEP00000007962 | ENSFHEP00000016432 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.980 |
LOC105920223 | ENSFHEP00000025839 | ENSFHEP00000023663 | ENSFHEP00000025839 | Malate synthase-like. | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase. | 0.978 |
LOC105920223 | LOC105920747 | ENSFHEP00000023663 | ENSFHEP00000006284 | Malate synthase-like. | Enoyl-CoA delta isomerase 2. | 0.981 |
LOC105920223 | acadsb | ENSFHEP00000023663 | ENSFHEP00000009973 | Malate synthase-like. | Acyl-CoA dehydrogenase short/branched chain. | 0.879 |