STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbc1d5TBC1 domain family, member 5. (870 aa)    
Predicted Functional Partners:
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.979
vps26a
VPS26, retromer complex component A.
   
 
 0.944
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.928
LOC105930120
Uncharacterized protein.
   
 
 0.850
vps26b
VPS26, retromer complex component B.
   
 
 0.850
pex3
Peroxisomal biogenesis factor 3.
      
 0.637
fkbp15
Peptidylprolyl isomerase.
   
  
 0.633
RAB41
RAB41, member RAS oncogene family.
   
 
 0.630
LOC105937589
RAB6B, member RAS oncogene family.
   
 
 0.630
rab6a
Uncharacterized protein.
   
 
 0.630
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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