STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSFHEP00000012984Uncharacterized protein. (306 aa)    
Predicted Functional Partners:
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.901
appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
 0.901
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.833
birc6
Baculoviral IAP repeat containing 6.
   
 0.766
mib2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.677
ripk4
Receptor-interacting serine-threonine kinase 4.
    
 0.630
cenpn
Centromere protein N.
   
 0.580
tradd
Tnfrsf1a-associated via death domain.
    
 0.547
cenpm
Proliferation associated nuclear element.
   
 0.546
cenpk
Uncharacterized protein.
    
 0.535
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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