STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sprtnSprT-like N-terminal domain. (460 aa)    
Predicted Functional Partners:
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
  0.983
LOC105927530
Protein phosphatase 2, regulatory subunit B'', beta.
   
    0.905
ppp2r3a
Protein phosphatase 2, regulatory subunit B'', alpha.
   
    0.905
LOC105929216
Spermatogenesis-associated 5 protein 1-like protein; Belongs to the AAA ATPase family.
   
 0.887
vcp
Valosin containing protein; Belongs to the AAA ATPase family.
   
 0.887
LOC105940225
Phosphatase and tensin homolog.
   
    0.855
LOC105915784
Transmembrane phosphatase with tensin homology.
   
    0.855
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
   
    0.855
spata5l1
Spermatogenesis associated 5-like 1.
   
 0.844
SPATA5
Spermatogenesis associated 5.
   
 0.844
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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