STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105928564Acid-sensing (proton-gated) ion channel 1a; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (485 aa)    
Predicted Functional Partners:
stoml1
Stomatin (EPB72)-like 1.
    
 0.703
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1.
    
 0.626
ENSFHEP00000008388
HECT domain-containing protein.
    
 0.626
ENSFHEP00000008781
HECT domain-containing protein.
    
 0.626
LOC105923572
NEDD4 like E3 ubiquitin protein ligase.
    
 0.626
hecw2
Uncharacterized protein.
    
 0.626
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
 0.626
ENSFHEP00000008750
C2 domain-containing protein.
    
 0.604
gak
Cyclin G associated kinase.
      
 0.561
LOC105925884
E3 ubiquitin-protein ligase.
    
  0.503
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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