snx8 protein (Fundulus heteroclitus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

snx8

Sorting nexin 8a. (521 aa)

Predicted Functional Partners:

gak

0.982

msh3

0.950

snx5

0.850

snx6

0.841

vps35

0.808

igf2r

0.794

ENSFHEP00000019910

0.777

vps29

0.754

LOC105924831

0.750

LOC105929287

0.750

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000019910	igf2r	ENSFHEP00000019910	ENSFHEP00000026595	Si:dkey-28n18.9.	Insulin-like growth factor 2 receptor.	0.706
ENSFHEP00000019910	snx8	ENSFHEP00000019910	ENSFHEP00000014672	Si:dkey-28n18.9.	Sorting nexin 8a.	0.777
ENSFHEP00000019910	vps29	ENSFHEP00000019910	ENSFHEP00000009224	Si:dkey-28n18.9.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.564
ENSFHEP00000019910	vps35	ENSFHEP00000019910	ENSFHEP00000005333	Si:dkey-28n18.9.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.574
LOC105924831	LOC105929287	ENSFHEP00000017016	ENSFHEP00000029088	AFP-like domain-containing protein.	N-acetylneuraminic acid synthase a.	0.893
LOC105924831	snx8	ENSFHEP00000017016	ENSFHEP00000014672	AFP-like domain-containing protein.	Sorting nexin 8a.	0.750
LOC105929287	LOC105924831	ENSFHEP00000029088	ENSFHEP00000017016	N-acetylneuraminic acid synthase a.	AFP-like domain-containing protein.	0.893
LOC105929287	snx8	ENSFHEP00000029088	ENSFHEP00000014672	N-acetylneuraminic acid synthase a.	Sorting nexin 8a.	0.750
gak	igf2r	ENSFHEP00000023046	ENSFHEP00000026595	Cyclin G associated kinase.	Insulin-like growth factor 2 receptor.	0.986
gak	snx8	ENSFHEP00000023046	ENSFHEP00000014672	Cyclin G associated kinase.	Sorting nexin 8a.	0.982
gak	vps29	ENSFHEP00000023046	ENSFHEP00000009224	Cyclin G associated kinase.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.543
gak	vps35	ENSFHEP00000023046	ENSFHEP00000005333	Cyclin G associated kinase.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.698
igf2r	ENSFHEP00000019910	ENSFHEP00000026595	ENSFHEP00000019910	Insulin-like growth factor 2 receptor.	Si:dkey-28n18.9.	0.706
igf2r	gak	ENSFHEP00000026595	ENSFHEP00000023046	Insulin-like growth factor 2 receptor.	Cyclin G associated kinase.	0.986
igf2r	snx5	ENSFHEP00000026595	ENSFHEP00000023121	Insulin-like growth factor 2 receptor.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.814
igf2r	snx6	ENSFHEP00000026595	ENSFHEP00000023662	Insulin-like growth factor 2 receptor.	Sorting nexin 6.	0.821
igf2r	snx8	ENSFHEP00000026595	ENSFHEP00000014672	Insulin-like growth factor 2 receptor.	Sorting nexin 8a.	0.794
igf2r	vps29	ENSFHEP00000026595	ENSFHEP00000009224	Insulin-like growth factor 2 receptor.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.459
igf2r	vps35	ENSFHEP00000026595	ENSFHEP00000005333	Insulin-like growth factor 2 receptor.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.493
msh3	snx8	ENSFHEP00000019572	ENSFHEP00000014672	MutS homolog 3 (E. coli).	Sorting nexin 8a.	0.950