STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ocrlOCRL inositol polyphosphate-5-phosphatase. (938 aa)    
Predicted Functional Partners:
sacm1l
SAC1 like phosphatidylinositide phosphatase a.
 
  
 0.978
synj1
Synaptojanin 1.
    
0.952
pik3c2a
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; Belongs to the PI3/PI4-kinase family.
     
 0.952
inpp4b
Inositol polyphosphate-4-phosphatase type II B.
     
 0.950
inpp5e
72 kDa inositol polyphosphate 5-phosphatase.
     
0.949
LOC105915567
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
  0.948
ENSFHEP00000032706
Uncharacterized protein.
    
  0.948
LOC105928444
Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b.
     
 0.947
plcg2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.946
LOC105940225
Phosphatase and tensin homolog.
   
 
 0.945
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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