STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gtf2bGeneral transcription factor IIB. (318 aa)    
Predicted Functional Partners:
polr2a
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.998
polr2b
Polymerase (RNA) II (DNA directed) polypeptide B; Belongs to the RNA polymerase beta chain family.
    
 0.997
POLR2E
DNA-directed RNA polymerases I, II, and III subunit RPABC1.
    
 0.997
gtf2f1
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
    
 0.995
polr2g
Polymerase (RNA) II (DNA directed) polypeptide G-like.
   
 0.994
ENSFHEP00000007488
RPOL4c domain-containing protein.
    
 0.994
ENSFHEP00000017931
Uncharacterized protein.
   
 0.994
gtf2e1
General transcription factor IIE, polypeptide 1, alpha.
    
 0.994
polr2c
Polymerase (RNA) II (DNA directed) polypeptide C.
    
 0.994
polr2f
Polymerase (RNA) II (DNA directed) polypeptide F.
    
 0.993
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.