STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105930248Caspase-8; Belongs to the peptidase C14A family. (385 aa)    
Predicted Functional Partners:
fadd
Uncharacterized protein.
   
 0.994
cflar
Uncharacterized protein; Belongs to the peptidase C14A family.
 
 
0.991
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
   
 0.990
tradd
Tnfrsf1a-associated via death domain.
    
 0.982
LOC105938713
Receptor-interacting serine-threonine kinase 3.
   
 0.972
LOC105918655
Uncharacterized protein; Belongs to the peptidase C14A family.
  
0.964
LOC105918367
Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family.
  
0.960
casp7
Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
0.957
casp6
Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.
   
0.955
LOC105921197
Uncharacterized protein.
   
 0.955
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.