STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdgThymine DNA glycosylase, tandem duplicate 1. (459 aa)    
Predicted Functional Partners:
sumo1
Small ubiquitin-related modifier.
    
 0.973
LOC105926274
Thymine DNA glycosylase, tandem duplicate 2.
  
  
 
0.923
sumo2
Small ubiquitin-related modifier.
   
 0.802
LOC105937167
Ubiquitin-like domain-containing protein.
   
 0.802
LOC105939042
Small ubiquitin like modifier 3.
   
 0.802
LOC105933585
Small ubiquitin-related modifier.
   
 0.802
gart
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
  
 
  0.797
ube2i
Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.767
LOC105916074
SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.766
apex1
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
  
 
 0.756
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.