STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cishCytokine inducible SH2 containing protein. (246 aa)    
Predicted Functional Partners:
eloc
Elongin C paralog a; Belongs to the SKP1 family.
    
 0.911
LOC105932814
Elongin B.
    
 0.848
ELOB
Transcription elongation factor B polypeptide 2.
    
 0.848
rnf7
Ring finger protein 7.
   
 0.839
CUL5
Cullin 5; Belongs to the cullin family.
   
 0.806
LOC105918278
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.806
LOC105924888
Cullin domain-containing protein; Belongs to the cullin family.
   
 0.806
prlr
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily.
    
 0.779
cul2
Cullin 2; Belongs to the cullin family.
    
 0.712
LOC105932753
Signal transducer and activator of transcription.
    
 0.704
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.