STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSFHEP00000017684USP domain-containing protein; Belongs to the peptidase C19 family. (214 aa)    
Predicted Functional Partners:
usp42
Ubiquitin specific peptidase 42; Belongs to the peptidase C19 family.
 
      0.900
suds3
SDS3 homolog, SIN3A corepressor complex component.
    
 0.727
CDC25B
M-phase inducer phosphatase 1.
    
 0.644
ENSFHEP00000020951
Uncharacterized protein.
     
 0.640
ENSFHEP00000033674
Ras converting CAAX endopeptidase 1b.
     
 0.640
LOC105930618
BRMS1 like transcriptional repressor b.
    
  0.633
brms1
BRMS1 transcriptional repressor and anoikis regulator.
    
  0.633
brms1l
Breast cancer metastasis-suppressor 1-like protein.
    
  0.633
LOC105934647
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.617
usp10
Ubiquitin carboxyl-terminal hydrolase.
     
 0.569
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.