STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frs2Fibroblast growth factor receptor substrate 2b. (522 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.944
ENSFHEP00000031486
Fibroblast growth factor receptor.
    
 0.849
LOC105928781
Fibroblast growth factor receptor.
    
 0.828
LOC105939348
Fibroblast growth factor receptor.
    
 0.821
fgfr3
Fibroblast growth factor receptor.
    
 0.821
LOC105917056
Fibroblast growth factor receptor.
    
 0.817
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.815
sos2
Son of sevenless homolog 2 (Drosophila).
   
 0.803
LOC105922347
Son of sevenless homolog 1 (Drosophila).
   
 0.803
ENSFHEP00000005656
Fibroblast growth factor receptor like 1a.
    
 0.773
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.