STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rasgrf2Ras protein-specific guanine nucleotide-releasing factor 2b. (1175 aa)    
Predicted Functional Partners:
LOC105939687
RAS related.
    
 0.959
mras
Muscle RAS oncogene homolog.
    
 0.958
LOC105939921
Zgc:55558.
    
 0.958
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
    
 0.956
rras2
RAS related 2.
    
 0.954
LOC105932314
Uncharacterized protein.
  
  
 
0.926
RASGRF1
Ras protein specific guanine nucleotide releasing factor 1.
  
  
 
0.923
grb2
Growth factor receptor-bound protein 2b.
   
 0.911
LOC105934114
Calcium channel, voltage-dependent, gamma subunit 8a.
    
  0.904
CACNG2
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
  0.904
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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