STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccdc6Coiled-coil domain containing 6a. (334 aa)    
Predicted Functional Partners:
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
     
 0.895
LOC105922677
Nuclear receptor coactivator 4.
     
 0.892
ppp4c
Serine/threonine-protein phosphatase.
    
 
 0.721
LOC105930061
Protein phosphatase 2, regulatory subunit A, beta b.
    
 
 0.679
ENSFHEP00000011248
Uncharacterized protein.
    
 
 0.623
ENSFHEP00000028485
Uncharacterized protein.
    
 
 0.623
LOC105934082
Coiled-coil domain containing 120.
      
 0.565
pdxdc1
Pyridoxal-dependent decarboxylase domain containing 1.
      
 0.552
ENSFHEP00000010610
Death domain-containing protein.
 
      0.547
ENSFHEP00000014400
Cwf21 domain-containing protein.
      
 0.543
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.