STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmmrHyaluronan-mediated motility receptor (RHAMM). (1044 aa)    
Predicted Functional Partners:
LOC105934899
Amyloid beta (A4) precursor protein b.
    
 0.785
APP
Amyloid beta precursor protein.
    
 0.785
aplp2
Amyloid beta (A4) precursor-like protein 2.
    
 0.743
aplp1
Amyloid beta (A4) precursor-like protein 1.
    
 0.726
mre11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
  0.677
sh3pxd2b
SH3 and PX domains 2B.
     
 0.657
rad50
RAD50 homolog, double strand break repair protein.
   
 0.639
prr12
Proline rich 12a.
      
 0.637
LOC105925210
Splicing factor, arginine/serine-rich 19.
      
 0.637
INSC
INSC spindle orientation adaptor protein.
      
 0.637
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.