STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)    
Predicted Functional Partners:
gtf2h4
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.999
ercc3
Excision repair cross-complementation group 3.
   
 0.998
gtf2h1
General transcription factor IIH, polypeptide 1.
    
 0.995
gtf2h3
General transcription factor IIH, polypeptide 3.
    
 0.995
ccnh
Cyclin H; Belongs to the cyclin family.
    
 0.993
ercc2
TFIIH basal transcription factor complex helicase XPD subunit.
    
 0.992
mnat1
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
    
 0.979
ENSFHEP00000020929
General transcription factor IIH, polypeptide 2.
    
 0.975
ENSFHEP00000034932
Ssl1 domain-containing protein.
    
 0.963
gtf2e1
General transcription factor IIE, polypeptide 1, alpha.
   
 0.960
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.