STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLXND1Plexin-D1. (1899 aa)    
Predicted Functional Partners:
sema3e
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; Belongs to the semaphorin family.
    
 0.813
nrp1
Neuropilin; Belongs to the neuropilin family.
    
 0.759
ENSFHEP00000005685
Semaphorin 7A; Belongs to the semaphorin family.
    
 0.706
LOC105936515
Si:ch211-113g11.6; Belongs to the semaphorin family.
    
0.699
LOC105930506
Sema domain-containing protein; Belongs to the semaphorin family.
    
 0.699
LOC105929026
Uncharacterized protein.
    
 0.677
LOC105939656
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.677
ENSFHEP00000024813
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl; Belongs to the semaphorin family.
    
 0.661
SEMA4D
Semaphorin 4D; Belongs to the semaphorin family.
    
 0.651
LOC105934596
Semaphorin 4e; Belongs to the semaphorin family.
    
0.643
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.