STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF146Ring finger protein 146. (360 aa)    
Predicted Functional Partners:
LOC105930968
Poly [ADP-ribose] polymerase.
    
 0.968
LOC105917316
Poly [ADP-ribose] polymerase.
    
 0.951
axin1
Axin 1.
    
 0.765
AXIN2
Axin 2.
    
 0.762
LOC105920126
Uncharacterized protein.
    
 0.762
chd1l
Chromodomain helicase DNA binding protein 1-like.
    
 
 0.755
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.749
ENSFHEP00000011861
RGS domain-containing protein.
    
 0.744
ank2
Uncharacterized protein.
    
 0.726
ankrd52
Ankyrin repeat domain 52a.
    
 0.726
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.