STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tjp2Tight junction protein 2a (zona occludens 2); Belongs to the MAGUK family. (785 aa)    
Predicted Functional Partners:
LOC105916256
Tight junction protein 1a; Belongs to the MAGUK family.
  
 
0.988
LOC105938527
Tight junction protein 1b; Belongs to the MAGUK family.
  
 
0.986
afdn
Afadin, adherens junction formation factor a.
   
 0.980
LOC105929382
F11 receptor, tandem duplicate 1.
   
 0.979
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2.
     
 0.965
LOC105936601
Uncharacterized protein.
 
  
  0.952
gja1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
   
 0.904
LOC105925165
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
 0.901
OCLN
Occludin.
   
 0.865
LOC105917368
Occludin a.
   
 0.865
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.