STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lgmnLegumain. (436 aa)    
Predicted Functional Partners:
cd74
CD74 molecule, major histocompatibility complex, class II invariant chain a.
     
 0.752
rps14
Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.
     
 0.742
ENSFHEP00000017245
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
     
0.741
ENSFHEP00000032469
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
     
0.741
ctsc
Cathepsin C; Belongs to the peptidase C1 family.
   
 
 0.735
mrps11
Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family.
     
 0.728
LOC105929532
Cathepsin Bb; Belongs to the peptidase C1 family.
   
 
 0.718
LOC105919722
Cathepsin Ba; Belongs to the peptidase C1 family.
   
 
 0.718
LOC105932234
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 
 0.687
ctsz
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 
 0.687
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.