STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSFHEP00000025289Apolipoprotein L, 1. (347 aa)    
Predicted Functional Partners:
ENSFHEP00000005309
Uncharacterized protein.
    
 0.876
ENSFHEP00000005371
Uncharacterized protein.
    
 0.876
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
     
 0.681
ENSFHEP00000031973
Lin-52 DREAM MuvB core complex component.
    
 0.534
lin54
Lin-54 DREAM MuvB core complex component.
    
 0.530
LOC105917477
Retinoblastoma binding protein 4.
    
 0.529
lin9
Lin-9 DREAM MuvB core complex component.
    
 0.528
RPA1
Uncharacterized protein.
    
 0.506
ENSFHEP00000021708
Si:ch211-66e2.5.
  
     0.506
rpa1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.506
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.