STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSFHEP00000027460B30.2/SPRY domain-containing protein. (268 aa)    
Predicted Functional Partners:
LOC105921197
Uncharacterized protein.
   
 0.588
LOC105928991
Death domain-containing protein CRADD.
  
  
 0.566
ripk2
Receptor-interacting serine-threonine kinase 2.
   
 0.566
rfx5
Regulatory factor X, 5.
    
 0.516
LOC105921325
NIMA-related kinase 7; Belongs to the protein kinase superfamily.
    
 0.514
rfxank
Regulatory factor X-associated ankyrin-containing protein.
    
 0.489
sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
    
 0.488
brcc3
BRCA1/BRCA2-containing complex, subunit 3.
    
  0.478
ripk4
Receptor-interacting serine-threonine kinase 4.
    
  0.461
LOC105938151
Interleukin-1.
   
 0.459
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.