STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbxl20F-box and leucine-rich repeat protein 20. (436 aa)    
Predicted Functional Partners:
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.984
ENSFHEP00000000227
Cullin 1b; Belongs to the cullin family.
    
 0.896
rabggtb
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
    
 
 0.859
ptar1
Protein prenyltransferase alpha subunit repeat containing 1.
    
 
 0.814
LOC105923405
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.796
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.796
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
     
 0.716
LOC105930277
NEDD8 ubiquitin like modifier.
    
 0.691
nedd8
NEDD8.
    
 0.691
cul2
Cullin 2; Belongs to the cullin family.
    
  0.689
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.