STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105916426Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)    
Predicted Functional Partners:
ptch2
Patched 2.
   
 0.990
ptch1
Patched 1.
   
 0.988
hhip
Hedgehog interacting protein.
    
 0.985
boc
BOC cell adhesion associated, oncogene regulated.
    
 0.979
cdon
Cell adhesion associated, oncogene regulated.
    
 0.979
disp1
Dispatched homolog 1 (Drosophila).
    
 0.954
ENSFHEP00000003609
Growth arrest-specific 1a.
    
 0.952
ENSFHEP00000009221
Uncharacterized protein.
    
 0.934
lrp2
Low density lipoprotein receptor-related protein 2a.
     
 0.907
LOC105939417
Low density lipoprotein receptor-related protein 2b.
     
 0.899
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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