ENSFHEP00000032256 protein (Fundulus heteroclitus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

ENSFHEP00000032256

Ig-like domain-containing protein. (104 aa)

Predicted Functional Partners:

uba52

0.558

LOC105938939

0.538

LOC105937894

0.507

cd79a

0.505

LOC105936529

0.497

plat

0.489

LOC105936728

0.489

LOC105926476

0.489

LOC105922290

0.485

ENSFHEP00000030017

0.484

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000030017	ENSFHEP00000032256	ENSFHEP00000030017	ENSFHEP00000032256	Uncharacterized protein.	Ig-like domain-containing protein.	0.484
ENSFHEP00000030017	LOC105937894	ENSFHEP00000030017	ENSFHEP00000009931	Uncharacterized protein.	B-cell antigen receptor complex-associated protein beta chain.	0.954
ENSFHEP00000030017	LOC105938939	ENSFHEP00000030017	ENSFHEP00000012229	Uncharacterized protein.	Tissue factor pathway inhibitor.	0.429
ENSFHEP00000030017	cd79a	ENSFHEP00000030017	ENSFHEP00000005847	Uncharacterized protein.	CD79a molecule, immunoglobulin-associated alpha.	0.957
ENSFHEP00000030017	uba52	ENSFHEP00000030017	ENSFHEP00000030704	Uncharacterized protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.419
ENSFHEP00000032256	ENSFHEP00000030017	ENSFHEP00000032256	ENSFHEP00000030017	Ig-like domain-containing protein.	Uncharacterized protein.	0.484
ENSFHEP00000032256	LOC105922290	ENSFHEP00000032256	ENSFHEP00000016125	Ig-like domain-containing protein.	SCY domain-containing protein.	0.485
ENSFHEP00000032256	LOC105926476	ENSFHEP00000032256	ENSFHEP00000027223	Ig-like domain-containing protein.	Uncharacterized protein.	0.489
ENSFHEP00000032256	LOC105936529	ENSFHEP00000032256	ENSFHEP00000007930	Ig-like domain-containing protein.	MCL1 apoptosis regulator, BCL2 family member b.	0.497
ENSFHEP00000032256	LOC105936728	ENSFHEP00000032256	ENSFHEP00000006669	Ig-like domain-containing protein.	Plasminogen activator, urokinase a; Belongs to the peptidase S1 family.	0.489
ENSFHEP00000032256	LOC105937894	ENSFHEP00000032256	ENSFHEP00000009931	Ig-like domain-containing protein.	B-cell antigen receptor complex-associated protein beta chain.	0.507
ENSFHEP00000032256	LOC105938939	ENSFHEP00000032256	ENSFHEP00000012229	Ig-like domain-containing protein.	Tissue factor pathway inhibitor.	0.538
ENSFHEP00000032256	cd79a	ENSFHEP00000032256	ENSFHEP00000005847	Ig-like domain-containing protein.	CD79a molecule, immunoglobulin-associated alpha.	0.505
ENSFHEP00000032256	plat	ENSFHEP00000032256	ENSFHEP00000006298	Ig-like domain-containing protein.	Plasminogen activator; Belongs to the peptidase S1 family.	0.489
ENSFHEP00000032256	uba52	ENSFHEP00000032256	ENSFHEP00000030704	Ig-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.558
LOC105922290	ENSFHEP00000032256	ENSFHEP00000016125	ENSFHEP00000032256	SCY domain-containing protein.	Ig-like domain-containing protein.	0.485
LOC105926476	ENSFHEP00000032256	ENSFHEP00000027223	ENSFHEP00000032256	Uncharacterized protein.	Ig-like domain-containing protein.	0.489
LOC105926476	LOC105938939	ENSFHEP00000027223	ENSFHEP00000012229	Uncharacterized protein.	Tissue factor pathway inhibitor.	0.666
LOC105936529	ENSFHEP00000032256	ENSFHEP00000007930	ENSFHEP00000032256	MCL1 apoptosis regulator, BCL2 family member b.	Ig-like domain-containing protein.	0.497
LOC105936728	ENSFHEP00000032256	ENSFHEP00000006669	ENSFHEP00000032256	Plasminogen activator, urokinase a; Belongs to the peptidase S1 family.	Ig-like domain-containing protein.	0.489

page 1 of 2

Network Stats

number of nodes:

3

number of edges:

2

average node degree:

1.33

avg. local clustering coefficient:

0.667

expected number of edges:

2

PPI enrichment p-value:

0.528

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031419

Cobalamin binding

5 of 13

2.03

2.83

9.75e-07

GO:0016866

Intramolecular transferase activity

5 of 19

1.86

2.51

2.40e-06

GO:0046872

Metal ion binding

7 of 491

0.6

0.36

0.0419

GO:0036094

Small molecule binding

7 of 512

0.58

0.35

0.0424

GO:0043167

Ion binding

9 of 859

0.46

0.31

0.0327

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2194

Cobalamin binding, and Glyoxalase-like domain

7 of 12

2.21

4.9

2.12e-11

CL:2196

Mixed, incl. Methylmalonyl-CoA mutase, and Glyoxalase-like domain

3 of 6

2.14

1.66

0.00062

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00280

Valine, leucine and isoleucine degradation

8 of 33

1.83

4.01

8.96e-12

map00640

Propanoate metabolism

7 of 36

1.73

3.24

1.14e-09

map00630

Glyoxylate and dicarboxylate metabolism

7 of 54

1.56

2.58

1.01e-08

map01200

Carbon metabolism

7 of 147

1.12

1.28

5.53e-06

map01120

Microbial metabolism in diverse environments

7 of 399

0.69

0.52

0.0031

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02310

B12 binding domain

4 of 8

2.14

2.36

2.00e-05

PF13468

Glyoxalase-like domain

2 of 3

2.27

0.85

0.0267

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036724

Cobalamin-binding domain superfamily

4 of 7

2.2

2.27

3.61e-05

IPR006158

Cobalamin (vitamin B12)-binding domain

4 of 7

2.2

2.27

3.61e-05

IPR006159

Methylmalonyl-CoA mutase, C-terminal

3 of 3

2.44

1.9

0.00028

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